Human skeletal muscle xenograft as a new preclinical model for muscle disorders
نویسندگان
چکیده
منابع مشابه
Human skeletal muscle xenograft as a new preclinical model for muscle disorders.
Development of novel therapeutics requires good animal models of disease. Disorders for which good animal models do not exist have very few drugs in development or clinical trial. Even where there are accepted, albeit imperfect models, the leap from promising preclinical drug results to positive clinical trials commonly fails, including in disorders of skeletal muscle. The main alternative mode...
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ژورنال
عنوان ژورنال: Human Molecular Genetics
سال: 2014
ISSN: 0964-6906,1460-2083
DOI: 10.1093/hmg/ddu028